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A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML.
<p>A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML. </p>
Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes.
<p>Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes. </p>
Bone marrow histology (Giemsa stain) of a patient showing an infiltrating Hodgkin's lymphoma on the left side. On the right side normal haematopoietic tissue can be seen.
<p>Bone marrow histology (Giemsa stain) of a patient showing an infiltrating Hodgkin's lymphoma on the left side. On the right side normal haematopoietic tissue can be seen.</p>
Howell-Jolly bodies in the cell adjacent to the granulocyte, spherocytes, polychromasia, and a single erythroblast in a case of auto-immune haemolytic anaemia (AIHA). (Howell-Jolly bodies are DNA remnants. Polychromatic cells still contain RNA.)
<p>Howell-Jolly bodies in the cell adjacent to the granulocyte, spherocytes, polychromasia, and a single erythroblast in a case of auto-immune haemolytic anaemia (AIHA). (Howell-Jolly bodies are DNA remnants. Polychromatic cells still contain RNA.)</p>
An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.
<p>An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.</p>
An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.
<p>An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.</p>
Round residual nucleus of purple-brown colour, circular, not refactive, eccentrically placed, frequently associated with acanthocytes, target cells or Pappenheimer bodies. Incidence: post splenectomy, severe anaemia with intact spleen function, e.g. pernicious anaemia, MDS
<p>Round residual nucleus of purple-brown colour, circular, not refactive, eccentrically placed, frequently associated with acanthocytes, target cells or Pappenheimer bodies. Incidence: post splenectomy, severe anaemia with intact spleen function, e.g. pernicious anaemia, MDS</p>
Incidental detection of Borrelia recurrentis (->) in a patient initially suspected to suffer from malaria. Borrelia recurrentis is transmitted by lice and ticks and is the causative agent of relapsing fever. Like malaria, relapsing fever often is a travel-related disease that, after an incubation time of up to 2 weeks, leads to fever attacks.
<p>Incidental detection of Borrelia recurrentis (->) in a patient initially suspected to suffer from malaria. Borrelia recurrentis is transmitted by lice and ticks and is the causative agent of relapsing fever. Like malaria, relapsing fever often is a travel-related disease that, after an incubation time of up to 2 weeks, leads to fever attacks.</p>
In the peripheral blood (May-Grünwald-Giemsa stain) of this 75-year old woman with PV all three cell lineages are increased: haemoglobin concentration 16 g/dL, white blood cell count 15,000/µL, platelet count 980,000/µL. In functional iron deficiency red blood cells often are microcytic. The MCV is only 75 fL. The haematopoietic cells of the patient show a JAK2 mutation.
<p>In the peripheral blood (May-Grünwald-Giemsa stain) of this 75-year old woman with PV all three cell lineages are increased: haemoglobin concentration 16 g/dL, white blood cell count 15,000/µL, platelet count 980,000/µL. In functional iron deficiency red blood cells often are microcytic. The MCV is only 75 fL. The haematopoietic cells of the patient show a JAK2 mutation.</p>