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<p>Fragmented red blood cells and thrombocytopenia in the case of a thrombotic thrombocytopenic purpura (TTP). In the partially thrombosed capillaries the red blood cells are exposed to a high degree of shearing force, which causes them to burst.</p>
<p>Blood film of a normal blood sample, which had frozen in the postbox. One can only recognise red blood cell 'shadows' or 'ghosts'.</p>
<p>Gametocyte in a patient infected with Plasmodium falciparum. </p>
<p>Bone marrow histology (periodic acid Schiff stain, PAS) displaying macrophages on the left, with a cytoplasm resembling crinkled parchment. They are so-called 'Gaucher' cells. Gaucher's disease is characterised by a congenital defect of the enzyme glucocerebrosidase leading to an increase of certain glycolipids (cerebrosides) inside the macrophages. On the right side of the picture the bone marrow appears normal.</p>
<p>Giant platelets have their name derived from their size exceeding the size of a normal red blood cell. </p>
<p>Giant platelet with prominent granulation from a patient with essential thrombocythaemia (ET). (Defective haematopoiesis causes detectable poikilocytosis.)</p>
<p>Peripheral blood (May-Grünwald-Giemsa stain) of a patient with essential thrombocythaemia, ET. Giant platelets (->) are frequently observed in this disease.</p>
<p>Granulated blasts have a size of 12 - 16 µm and show significant reddish granules in their cytoplasm. The shape of the nucleus is round or oval with a very high nucleocytoplasmic ratio of 70 – 95%. </p> <p>The chromatin is predominantly regularly distributed and neither clumped nor condensed. The nucleus has a varying number of nucleoli which may be hidden by the chromatin. </p>
<p>Granulated blasts have a size of 12 – 16 µm and show significant reddish granules in their cytoplasm. The shape of the nucleus is round or oval with a very high nucleocytoplasmic ratio of 70 – 95%. </p> <p>The chromatin is predominantly regularly distributed and neither clumped nor condensed. The nucleus has a varying number of nucleoli which may be hidden by the chromatin. </p>